|
|
androsterone + NADP+ <=> 5alpha-androstane-3,17-dione + NADPH + H+
|
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.112
indanol dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.21
aldose reductase
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
|
–
–
–
–
–
–
–
–
–
–
|
MK
|
|
BRENDA:
BR29252;
BS372395
KEGG:
R02477
MetaCyc:
1.1.1.209-RXN
SABIO-RK:
2409
|
|
|
|
androsterone + NAD+ <=> 5alpha-androstane-3,17-dione + NADH + H+
|
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.112
indanol dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.210
3beta(or 20alpha)-hydroxysteroid dehydrogenase
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
|
–
–
–
–
–
–
–
–
–
–
|
K
|
|
BRENDA:
BR29252-a;
BS186973
KEGG:
R02476
MetaCyc:
1.1.1.209-RXN_WOP
SABIO-RK:
2408
|
|
|
|
epiandrosterone + NAD+ <=> 5alpha-androstane-3,17-dione + NADH
|
1.1.1.145
3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.210
3beta(or 20alpha)-hydroxysteroid dehydrogenase
1.1.1.239
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
|
–
–
–
–
–
–
|
K
|
|
BRENDA:
BS188512;
BS257033
KEGG:
R09956
SABIO-RK:
13781;
14581
|
|
|
|
5alpha-androstane-3,17-dione + acceptor <=> 4-androstene-3,17-dione + reduced_acceptor
|
1.3.99.5
3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
|
–
|
MK
|
|
KEGG:
R01834
MetaCyc:
RXN-12124
|
|
|
|
5alpha-androstane-3,17-dione + NADPH <=> epiandrosterone + NADP+
|
1.1.1.145
3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
|
–
–
–
–
–
|
|
|
BRENDA:
BS188021
SABIO-RK:
11637
|
|
|
|
5alpha-dihydrotestosterone + NADP+ <=> 5alpha-androstane-3,17-dione + NADPH
|
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62
17beta-estradiol 17-dehydrogenase
1.1.1.64
testosterone 17beta-dehydrogenase (NADP+)
1.3.1.20
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
|
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS188305;
BS384190
SABIO-RK:
11795
|
|
|
|
5alpha-androstane-3,17-dione + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+
|
1.3.1.22
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
|
–
|
K
|
|
KEGG:
R10242
SABIO-RK:
14506
|
|
|
|
5alpha-androstane-3,17-dione + 2 reduced_ferredoxin_[iron-sulfur]_cluster + 2 H+ + O2 <=> 9alpha-hydroxy-5alpha-androstane-3,17-dione + 2 oxidized_ferredoxin + H2O
|
1.14.15.30
3-ketosteroid 9alpha-monooxygenase
|
–
|
|
|
BRENDA:
BS418332
|
|
|
|
5alpha-androstane-3,17-dione + 2,6-dichlorophenolindophenol <=> 5beta-androst-1-en-3,17-dione + reduced_2,6-dichlorophenolindophenol
|
1.3.99.4
3-oxosteroid 1-dehydrogenase
|
–
|
|
|
BRENDA:
BS396035
|
|
|
|
5alpha-dihydrotestosterone + NADH <=> 5alpha-androstane-3,17-dione + NAD+
|
1.1.1.62
17beta-estradiol 17-dehydrogenase
|
–
|
|
|
BRENDA:
BS188486
|
|
|
|
5alpha-androstane-3,17-dione + NADH <=> 5alpha-Androstan-3alpha-ol-17-one + NAD+
|
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
–
|
|
|
BRENDA:
BS396037
|
|
|
|
5alpha-pregnan-17alpha-ol-3,20-dione + reduced_flavodoxin + O2 <=> 5alpha-androstane-3,17-dione + acetate + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS432573
|
|
|
|
5alpha-dihydrotestosterone + NADPH + H+ <=> 5alpha-Androstane-3beta,17beta-diol + 5alpha-androstane-3,17-dione + NADP+
|
1.1.1.62
17beta-estradiol 17-dehydrogenase
|
–
|
|
|
BRENDA:
BS425809
|
|
|
|
5alpha-dihydrotestosterone + NADPH <=> 5alpha-androstane-3,17-dione + NADP+
|
1.1.1.62
17beta-estradiol 17-dehydrogenase
|
–
|
|
|
BRENDA:
BS188487
|
|
|
|
5alpha-androstane-3,17-dione + NADPH + H+ <=> 5alpha-Androstan-3alpha-ol-17-one + NADP+
|
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
|
–
|
|
|
BRENDA:
BS387623
|
|
|
|
5alpha-androstane-3,17-dione + N,N,N'',N''-tetramethyl-1,4-phenylendiamine <=> 4-androstene-3,17-dione + reduced_N,N,N'',N''-tetramethyl-1,4-phenylendiamine
|
1.3.99.5
3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
|
–
|
|
|
BRENDA:
BS451556
|
|